Pre Diabetes and Obesity – New Study Supports Red Wine and Supplements

Pre diabetes and obesity are associated with type 2 diabetes. In fact, it is likely that pre diabetes will soon be classified as a health condition and not just a precursor of the health problem which is type 2 diabetes.

A recent study from Austria showed that several red wines contained rosiglitazone, a natural compound that is being marketed by the drug firm Smith-Cline. In fact, the levels of rosiglitazone were higher in the wines than the recommended therapeutic dose contained in the pills used to treat type 2 diabetes.

These beneficial effects were seen in red wine only. Additionally, the high levels of this protective compound were not seen in all red wines. As background, the researchers note that these wines have shown the ability to prevent the development of type 2 diabetes to some extent. The molecular reactions and pathways involved in this protection are not fully understood at this time.

Obesity and pre diabetes both have problems with cellular inflammation. These wines contain substantial amounts of ligands. Ligands help the body reduce inflammation, thin the blood and prevent clots as well as assist in cholesterol transport and metabolism. Ligands are “sticky” molecules. Ligands attach to the circulating cholesterol which assist the cholesterol in its journey to the liver where it is metabolized.

Red wine should not be considered an alternative to standard therapy when it comes to treating pre diabetes, obesity and type 2 diabetes. The same can be said for prevention of these conditions. No one knows what the effects of alcohol would be in the presence of these ligands and polyphenol antioxidants. in their study, the researchers did find that all the red wines had some of these protective compounds.

As for rosiglitazone, there have been some legal issues and even lawsuits regarding its use. This does put a cloud over the use of rosiglitazone in large patient populations.

The study seems to make the case for some wines and that elusive “something” that seems to extend life. The beneficial effects of wine have been touted as the major contributor to the French Effect. The French Effect is the association of longevity with a high-fat diet. This association is perplexing as it defies conventional thinking. It does appear that with studies and research findings such as the ones we have discussed, we are a little closer to understanding the beneficial effects of red wine. It is fair to say that some wines have been shown to contain compounds that positively impact on some health conditions. Undoubtedly, we will be hearing more about wine in the near future.